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    Regenetek’s Combination Stem Cell and Vascular Therapy

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    ‎The Most Current Information Available from Leading Scientists and Clinical Trials World-wide

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    Application of Technology to Make Any Size of Study Self-Managing and Affordable

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  • Neurodegenerative Disorders

    The Latest Updates on Diseases Treatable Through Regenerative Medicine

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    Opinions from Regenetek and Leading Authorities in Regenerative Medicine

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About: Doug Broeska

Doug Broeska is a PhD Medical Researcher and CEO of Regenetek Inc, a Canadian Biotech Research firm working with several hospitals and clinics world-wide to develop medical procedural protocols for neurodegenerative disease management.

Recent Posts by Doug Broeska

Introductory word

Hundreds of thousands of undocumented therapies occur in clinics world-wide each year under the label of ‘medical tourism’. Even if physicians in these clinics wanted to follow their patients, there has been no method of doing so. Until now. Regenetek Research recognizes that there is a high need for a method and a study design that provides proof of both safety and efficacy for new treatment interventions such as autologous stem cell therapies or unsanctioned vascular surgeries. These types of medical interventions present viable choices for patients beyond conventional drug therapies that only treat symptoms. My goal in writing these articles is to point out the gaps in the research while we look for the truth, not reinforce the biases in the science.

WHAT CAN I TAKE? MS Patient’s Medication List Pre and Post Stem Cell Treatment

For the researchers conducting this study, this is the most often asked question of all. When we started this research study a number of years ago, we didn’t know the answer because information on how chemical medications and supplements would affect the function of stem cells just wasn’t available. At the time, we knew of a few medications that would definitely be harmful to stem cell activity and we thought the list was fairly short. But research sheds light on new discoveries over time and in many instances serendipitously uncovers information that is unexpected and or different from the hypothesis or expected outcome. In research this is known as a ‘paradoxical effect’; a reaction opposite to that which was predicted or anticipated. So it is with this study. Since much of what we are doing in this study is being done for the first time in history, this is not surprising. As a result of this research, there are a great number of ‘medical firsts’ in the queue to be published. For example, for the first time in history we have seen the transition of skeletal muscle from spastic to flaccid tissue once the neural pathways begin to re-establish signalling. This is because no patient with the type of paralysis left by a chronic debilitating disease such as MS has ever gone far enough into a healing recovery to experience these changes. We have also seen imaging changes post-therapy in lesions within the brain, so significant that these bright white appearing foci have actually vanished without a trace, as reported by neurologists. In order to study this area more completely, we have now engaged a top neuroscientist in this area of research.

Proof that STAP Cells Can Kill

Stimulus-triggered acquisition of pluripotency or STAP was supposed to be the new medical breakthrough based on the science of stimulating any old human cells to become pluripotent stem cells by treating them with certain growth factors, acidic baths, or other manipulation. This technological leap forward would mean that ordinary blood cells for instance, could be treated to become neurons in the brain, etc, and such a discovery could lead to cures for Alzheimer’s and MS among many other diseases. STAP would have been a much easier way to produce stem cells than current methods as neither nuclear transfer nor transcription factors would have been necessary in their growth. But the ‘science of STAP’ is turning out to be the present day equivalency of alchemy, the notion that lead can be turned into gold.

Subject David Echt’s Case in Retrospect

To provide some background here for David Echt’s post, 6 months after treatment in March of 2014, David wasn’t experiencing the recovery we are seeing in other patient/subjects over the same time period, post-therapy. Although there were some important improvements, there was no functional difference in his affected right leg whatsoever; it was still as paralyzed as it had been for the past 6 years. This didn’t make a lot of sense to us. We knew he was on Metformin for his diabetes, but as far as we knew, that shouldn’t have interfered with the activity of the stem cells…OR SO WE THOUGHT. Then we came across a new article entitled ‘The paradoxical effect of metformin on endothelial cells and angiogenesis’. The research concluded that the drug Metformin would have precisely the OPPOSITE effect of what would be expected. Instead of fostering stem cell activity and endothelial growth, it INHIBITED these growth activities, which was a stunning surprise to the researchers. Metformin would therefore inhibit the formation of capillary networks, negate the trophic effect of stem cells in the brain, and likely disrupt endothelial, myelin and neuronal growth. So despite what we THOUGHT WE KNEW, many drug interactions with stem cells are difficult to make recommendations about these drugs because there has not been enough work done in this area of study. It really requires a deep dive into medical journals. What we are witnessing with David’s dramatic demonstration is real medical pioneering stuff. And now we know a couple more things. Because David’s recovery has now resumed, we have a good demonstration of the lasting effect of the ‘type’ of stem cells (mesenchymal neural progenitor cells or ‘true stem cells’) we’re typing, isolating, and colonizing for reinfusion.

Chemotherapy with Stem Cells, HSCT for MS is Wrong AND Dangerous

Notice To readers:

As a result of a backlash by supporters of Hematopoietic stem cell transplantation for multiple sclerosis, I have modified this post and intend to produce the evidence that supports my opinion-based assertions through clinical study evidence and links within the finished article.